Link to our ongoing European clinical Ph IIb trial in Parkinson´s disease dyskinesia (NCT03956979)
CP-012 |
About CP-012Levodopa is the gold-standard for treatment in Parkinson`s disease, but patients often need to administer up to 6-8 doses daily due to its short half-life and wearing-off. Since frequent dosing is not possible at nighttime, around 60% of patients suffer from disabling nocturnal and early morning muscle stiffness known as early morning akinesia. Furthermore, patients may experience a delayed onset of action with the first morning dose of Levodopa, which increases and extends their morning disability. There is currently no efficient therapy available for early morning akinesia. We are developing CP-012 in collaboration with BDD Pharma as a novel formulation of levodopa and carbidopa to be taken ad bedtime in addition to normal medication and prevent the onset of nocturnal symptoms and early morning akinesia. Contera Pharma has full ownership and holds global rights to the program. |
Neuroinflammation |
About NeuroinflammationRecent clinical and preclinical studies point towards a critical role for neuroinflammation in the development of movement disorders including Parkinson’s disease. With the University of Copenhagen, we investigate glial biology involvement in disease by utilizing state-of-the-art bioengineering tools to enable the identification of novel drug targets for us to pursue in our continued efforts to develop better treatment options for patients. |
Discovery |
Work in progress |